Oral Microbiota and Muscle Function in the Ageing Subject

Oral Microbiota and Muscle Function in the Ageing Subject: MYOBIOTA Study

Promoteur : University Hospital, Rouen

Titre et résumé fournis en anglais par le registre source, reproduits sans traduction ni interprétation.

Ageing of the general population may be a risk factor for various complications, including sarcopenia. Sarcopenia is a progressive loss of muscle mass and muscle strength, leading to a decrease in functional capacities. It affects between 0.7% and 16% of European adults over 70 years of age (1). Recent studies suggest that the faecal microbiota may be altered with ageing but also according to sarcopenic status. Furthermore, no study has currently published data on the relationship between salivary microbiota and sarcopenic status. The main hypothesis of this study is that a decrease in salivary microbiota richness could be associated with impaired handgrip strength in the ageing subject.